Tauro-β-muricholic acid sodium
Tauro-Beta(β)-Muricholic Acid Sodium Salt
CAS: 145022-92-0
Molecular Formula: C26H44NNaO7S
Tauro-β-muricholic acid sodium - Names and Identifiers
Tauro-β-muricholic acid sodium - Physico-chemical Properties
| Molecular Formula | C26H44NNaO7S |
| Molar Mass | 537.69 |
| Melting Point | 120-125oC |
| Water Solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| Appearance | Shape Solid Color White to Pale Beige |
| Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Stability | Hygroscopic |
| Use | Tauro-β-muricholic Acid sodium (T-βMCA sodium) is an endogenous metabolite, a competitive and reversible FXR antagonist, with an IC50 value of 40 μM. |
Tauro-β-muricholic acid sodium - In vitro study
T-βMCA sodium inhibits FXR reporter activity in the CRC cell line HT29 (EC 50 ~10 μM).
T-βMCA sodium dose-dependently increases WNT signaling in HT29 and HCT116 cells.
T-βMCA sodium induces proliferation and DNA damage in Lgr5 cells.
Last Update：2024-04-10 22:29:15
Tauro-β-muricholic acid sodium - Target
IC50: 40 μM (FXR)
Last Update：2024-04-09 20:52:54
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Product Name: T-βMCA sodium Visit Supplier Webpage Request for quotationCAS: 145022-92-0
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Tauro-β-muricholic acid sodium Visit Supplier Webpage Request for quotationCAS: 145022-92-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Tauro β-Muricholic Acid Sodium Salt Visit Supplier Webpage Request for quotationCAS: 145022-92-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
Tauro-β-muricholic acid sodium
TENSOPOL 94(R)
Einecs 286-045-9
5-溴-3-氯吡啶-2-甲腈
3-iodo-1-hydroxypropan-2-one
Alcaftadine (R89674)
(1S,5S,6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-one
Gynuramide II
2,4-DINITRO-6-(1-METHYLHEPTYL)PHENOL
对氨基苯酚硫酸盐
TENSOPOL 94(R)
Einecs 286-045-9
5-溴-3-氯吡啶-2-甲腈
3-iodo-1-hydroxypropan-2-one
Alcaftadine (R89674)
(1S,5S,6R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-one
Gynuramide II
2,4-DINITRO-6-(1-METHYLHEPTYL)PHENOL
对氨基苯酚硫酸盐